PEX5 Antibody - BSA Free

Western Blot: PEX5 Antibody [NBP1-32782] - Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE, antibody diluted at 1:5000.

Immunohistochemistry-Paraffin: PEX5 Antibody [NBP1-32782] - Paraffin-embedded hepatoma. PEX5 antibody dilution: 1:500.

Western Blot: PEX5 Antibody [NBP1-32782] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PEX5 antibody (NBP1-32782) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

• Reactivity: Hu, Mu, Bv, Gp
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PEX5 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PEX5 Antibody - BSA Free (NBP1-32782) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PEX5. The exact sequence is proprietary.
• Localization: Cytoplasm, Peroxisome membrane, Peripheral membrane protein
• Predicted Species: Bovine (97%), Guinea Pig (98%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PEX5
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:1000-1:10000
• Theoretical MW: 71 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for PEX5 Antibody - BSA Free

• FLJ50634
• FLJ50721
• Peroxin-5
• peroxisomal biogenesis factor 5
• Peroxisomal C-terminal targeting signal import receptor
• peroxisomal targeting signal 1 receptor
• peroxisomal targeting signal import receptor
• peroxisomal targeting signal receptor 1
• Peroxisome receptor 1peroxin-5
• PTS1 receptor
• PTS1-BP
• PTS1RFLJ51948
• PXR1peroxisomal targeting signal 1 (SKL type) receptor

Background

The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: PEX5
• Entrez:
  • 5830(Human)
• Uniprot:
  • P50542(Human)