PEX26 Antibody

Western Blot: PEX26 Antibody [NBP1-52048] - NBP1-52048 (0.5ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

PEX26 Antibody Summary

• Description: Novus Biologicals Goat PEX26 Antibody (NBP1-52048) is a polyclonal antibody validated for use in WB and ELISA. Anti-PEX26 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-QKPNLEGSVSHK corresponding to internal region according to NP_060399.1.
• Epitope: C-QKPNLEGSVSHK
• Specificity: Reported variants represent identical protein: NP_060399.1, NP_001121121.1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: PEX26
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:64000
  • Western Blot 0.5 - 1.5 ug/ml
• Application Notes: WB: Approx. 33 kDa band observed in human kidney lysates (calculated MW of 33.9 kDa band according to NP_060399.1).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PEX26 Antibody

• FLJ20695
• peroxin-26
• peroxisomal biogenesis factor 26
• peroxisome assembly protein 26
• peroxisome biogenesis disorder, complementation group 8
• peroxisome biogenesis disorder, complementation group A
• peroxisome biogenesis factor 26
• PEX26M1T
• Pex26pM1T

Background

This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Two transcript variants encoding the same protein have been identified for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PEX26 Antibody (NBP1-52048)(1)

Publication using NBP1-52048

• Yik WY, Steinberg SJ, Moser AB et al. Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders. Hum Mutat 2009-03-01 [PMID: 19105186]

Bioinformatics

• Gene Symbol: PEX26
• Entrez:
  • 55670(Human)
• Uniprot:
  • NP_060399.1(Human)