PEX1 Antibody

Western Blot: PEX1 Antibody [NBP1-49881] - Staining of Mouse Liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Mu, Rt, Hu, Bv, Ca
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

PEX1 Antibody Summary

• Immunogen: Peptide with sequence C-QAKESTFPKEGDAH corresponding to internal region according to Uniprot Mouse NP_082053.1.
• Epitope: QAKESTFPKEGDAH - internal region
• Predicted Species: Human (100%), Canine (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: PEX1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 0.3 - 1 ug/ml
• Application Notes: WB: Approx. 150 kDa band observed in mouse and rat liver lysates (calculated MW of 137 kDa band according to NP_082053.1).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PEX1 Antibody

• peroxin-1
• peroxisomal biogenesis factor 1
• Peroxisome biogenesis disorder protein 1
• peroxisome biogenesis factor 1
• Zellweger syndrome 1
• Zellweger syndrome
• ZWS
• ZWS1

Background

This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PEX1 Antibody (NBP1-49881)(1)

Publication using NBP1-49881

• Yik WY, Steinberg SJ, Moser AB et al. Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders. Hum Mutat 2009-03-01 [PMID: 19105186]

Bioinformatics

• Gene Symbol: PEX1
• Entrez:
  • 71382(Mouse)
  • 500006(Rat)
• Uniprot:
  • NP_082053.1(Mouse)