Peptide YY Antibody (PYY) [Biotin]

Product Discontinued

Peptide YY Antibody (PYY) [Biotin] Summary

• Immunogen: Synthetic human PYY adsorbed onto aluminum hydroxide gel
• Specificity: This antibody binds human PYY. Cross-reactivity with NPY or PP in solution is <0.1%.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PYY
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 10 mM Phosphate buffer (pH 7.4) and 0.5 M NaCl
• Preservative: 0.09% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Peptide YY Antibody (PYY) [Biotin]

• Peptide tyrosine tyrosine
• Peptide YY
• Peptide-YY
• PYY
• PYY1
• PYY-I

Background

Peptide tyrosine-tyrosine (PYY) amide is a 36 amino-acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PYY