ICC/IF reactivity reported in (PMID: 21559457). Detects a band of approximately 90-93 kDa in rat brain and rat pancreas samples. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
cAMP and cAMP-inhibited cGMP 3'-5'-cyclic phosphodiesterase 10A
dJ416F21.1 (phosphodiesterase 10A)
phosphodiesterase 10A1 (PDE10A1)
One of the many phosphodiesterases that compartmentalize and hydrolyze cAMP and cGMP into AMP and GMP is PDE10. Only one member of the cAMP and cGMP-specific PDE10 family has been cloned and characterized. The PDE10A gene is expressed in at least two variant forms (PDE10A1, PDE10A2) generated by RNA splicing and/or the use of alternate initiation sites. PDE10A is widely expressed in the putamen and caudate nucleus in the brain, thyroid and testis. The expression of PDE10A is also abundant in Heart.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for PDE10A Antibody (NB300-645). (Showing 1 - 1 of 1 FAQs).
This website claims that Tian et al (2011) successfully used this Pde10A antibody. However, in this paper they say the antibody that they used is from Scottish Biomedical. Is the antibody that you are selling here the same as they used, just now available from Novus rather than Scottish Biomedical?
I pulled up that article and it in fact does cite Novus as the antibody source. If you read into the Immunocytochemistry section, or do a search on the article for the word Novus it will come up. I believe the Scottish Biomedical reference is for the BSA.
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PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.