Species: Hu, Mu, Rt, Pm
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
One of the many phosphodiesterases that compartmentalize and hydrolyze cAMP and cGMP into AMP and GMP is PDE10. Only one member of the cAMP and cGMP-specific PDE10 family has been cloned and characterized. The PDE10A gene is expressed in at least two variant forms (PDE10A1, PDE10A2) generated by RNA splicing and/or the use of alternate initiation sites. PDE10A is widely expressed in the putamen and caudate nucleus in the brain, thyroid and testis. The expression of PDE10A is also abundant in Heart.
Bioinformatics
| Uniprot |
Human |
| Product By Gene ID |
10846 |
| Alternate Names |
- cAMP and cAMP-inhibited cGMP 3'-5'-cyclic phosphodiesterase 10A
- dJ416F21.1 (phosphodiesterase 10A)
- EC 3.1.4
- EC 3.1.4.17
- EC 3.1.4.35
- FLJ11894
- FLJ25677
- HSPDE10A
- phosphodiesterase 10A
- phosphodiesterase 10A1 (PDE10A1)
|