Recombinant Human PDCD6 Protein

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SDS-Page: Recombinant Human PDCD6 Protein [NBP1-51048] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human PDCD6 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-191 of Human PDCD6

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
PDCD6
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
10mM sodium citrate(pH 3.5) containing 40% glycerol
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human PDCD6 Protein

  • ALG2
  • ALG-2
  • Apoptosis-linked gene 2 protein
  • apoptosis-linked gene-2
  • FLJ46208
  • MGC111017
  • MGC119050
  • MGC9123
  • PDCD6
  • PEF1B
  • Probable calcium-binding protein ALG-2
  • programmed cell death 6
  • programmed cell death protein 6

Background

Programmed cell death 6, also known as PDCD6, is calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Recombinant human PDCD6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol PDCD6
Entrez