PCBD2 Antibody - BSA Free

Western Blot: PCBD2 Antibody - BSA Free [NBP3-47214] - Human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with (PCBD2 antibody) at dilution of 1:500

• Reactivity: Hu, Mu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PCBD2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PCBD2 Antibody - BSA Free (NBP3-47214) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha(TCF1) 2. (Uniprot# Q9H0N5)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PCBD2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500-1:2000
• Theoretical MW: 14 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PCBD2 Antibody - BSA Free

• 4-alpha-hydroxy-tetrahydropterin dehydratase 2
• DCOH2DCOHMPHS2,6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocytenuclear factor 1 alpha (TCF1) 2
• DcoH-like protein DCoHm
• dimerization cofactor of hepatocyte nuclear factor 1 (HNF1) from muscle
• dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
• Dimerization cofactor of hepatocyte nuclear factor 1 from muscle
• EC 4.2.1.96
• HNF-1-alpha dimerization cofactor
• PHS 2
• pterin-4 alpha-carbinolamine dehydratase 2
• pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocytenuclear factor 1 alpha (TCF1) 2
• pterin-4-alpha-carbinolamine dehydratase 2

Background

PCBD2, also known as Pterin-4-alpha-carbinolamine dehydratase 2, is a 130 amino acid protein that is 14 kDa, involved in tetrahydrobiopterin biosynthesis preventing the formation of 7-pterins and accelerating the formation of quinonoid-BH2, also being known to regulate the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity. The protein is being studied for its involvement in hyperphenylalaninemia. The PCBD2 has also been shown to have interactions with DYRK1B, AATF, ASCC2, C1D, and CHAF1A in pathways such as phenylalanine degradation I (aerobic) pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCBD2