PAR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: PAR2 Antibody [NBP1-44306] - Analysis of anti-F2RL1 antibody with human kidney.

• Reactivity: Hu, Mu, Rt, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

PAR2 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 18 amino acid peptide from 2nd extracellular domain of human PAR2.
• Epitope: 2nd extracellular domain
• Specificity: Human PAR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NMBR (39%).
• Predicted Species: Mouse (94%), Rat (94%), Primate (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: F2RL1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
• Application Notes: Use in Immunohistochemistry reported in scientific literature (PMID 27457091)..

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (94%), Gorilla (89%), Equine (89%), Porcine (89%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PAR2 Antibody - BSA Free

• CFIIRL1
• coagulation factor II (thrombin) receptor-like 1
• Coagulation factor II receptor-like 1
• F2RL1
• GPCR11
• GPR11protease-activated receptor 2
• G-protein coupled receptor 11
• PAR2
• PAR-2
• PAR2G protein-coupled receptor-11
• proteinase-activated receptor 2
• proteinase-activated receptor-2
• Thrombin receptor-like 1

Background

The Proteinase-activated receptor 2 (PAR2) is a member of the proteinase-activated receptor subfamily. It is activated through proteolytic exposure of an occult tethered ligand by trypsin and trypsin-like proteases. This is in contrast to other members of the subfamily which are activated by the protease thrombin. PAR2 has been implicated in acute inflammatory response, asthma, and pain transmission. PAR2 expression has been documented in the periphery. ESTs have been isolated from adrenal, brain, breast, heart/melanocyte/uterus, kidney, lung, and vessel libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PAR2 Antibody (NBP1-44306)(1)

Publication using NBP1-44306

• Pan R, Zhang Y, Zang B et al. Hydroxysafflor yellow A inhibits TGF-beta1-induced activation of human fetal lung fibroblasts in vitro J. Pharm. Pharmacol. 2016-07-26 [PMID: 27457091] (IF/IHC, Human)

FAQs for PAR2 Antibody (NBP1-44306). (Showing 1 - 1 of 1 FAQ).

1. Would you be able to supply the blocking peptide for antibody NBP1-44306? If yes, what would be the catalog number and price for this peptide ? If no, could you provide the sequence so that we'll be able to make it custom for her?
   • This blocking peptide can be made available for purchase. The blocking peptide will be $190 and can be ordered with the product number NBP1-44306PEP.

Bioinformatics

• Gene Symbol: F2RL1