PAQR8 Antibody

Product Discontinued

PAQR8 Antibody Summary

• Immunogen: A protein specific peptide conjugated to KLH recognizing intracellualar epitopes.
• Localization: Cell Membrane. Multi-pass membrane protein. Note: Colocalizes with a lysosomal protein cathepsin D.
• Specificity: Progestin Receptor beta
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PAQR8
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
  • Western Blot 1:100-1:2000
• Application Notes: By Western blot it detects a 40 kDa protein representing PR beta.

Reactivity Notes

This antibody is reactive against Porcine, Rat, Mouse and Human.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: 0.05% Sodium Azide
• Purity: Unpurified

Alternate Names for PAQR8 Antibody

• C6orf33Lysosomal membrane protein in brain 1
• LMPB1FLJ32521
• lysosomal membrane protein in brain-1
• membrane progestin receptor beta
• mPR beta
• MPRBFLJ46206
• Progestin and adipoQ receptor family member 8
• progestin and adipoQ receptor family member VIIIchromosome 6 open reading frame 33

Background

Progestin Receptor Beta-Intra recognizes the intracellular epitope of the membrane progestin receptor. Progestin receptors with are found in pituitary, reproductive tract and most estrogen receptor-containing brain regions; these receptors are inducible by estrogen treatment. There are also progestin receptor sites in brain areas lacking estrogen receptors, such as the cerebral cortex of the rat; these receptors are not induced by estradiol treatment. Nevertheless, such receptors resemble those induced by estradiol. Another inducer of progestin receptors in brain is testosterone, which works through its conversion to estradiol via aromatization

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PAQR8
• Entrez:
  • 85315(Human)
  • 74229(Mouse)
  • 316275(Rat)