Pancreatic Polypeptide/PP Antibody

Product Discontinued

Pancreatic Polypeptide/PP Antibody Summary

• Immunogen: Synthetic human pancreatic polypeptide conjugated to KLH.
• Localization: Cytoplasmic
• Specificity: This antibody reacts with pancreatic polypeptide. It stains the periphery of islets, exocrine pancreatic parenchyma and the epithelium of small and medium sized ducts and acinar cells.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PPY
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Whole antisera
• Preservative: Sodium Azide
• Purity: Unpurified

Alternate Names for Pancreatic Polypeptide/PP Antibody

• INN
• Obinepitide
• pancreatic polypeptide (ppy)
• pancreatic polypeptide PNPPP
• pancreatic polypeptide Y
• Pancreatic Polypeptide
• pancreatic prohormone
• PNP
• PP
• PPY

Background

Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma levels of this hormone have been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPY
• Entrez:
  • 5539(Human)