Pancreatic Polypeptide/PP Antibody (6) - BSA Free

Product Discontinued

Pancreatic Polypeptide/PP Antibody (6) - BSA Free Summary

• Immunogen: Synthetic human PP
• Specificity: Binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PPY
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:3000
  • Western Blot
• Application Notes: ELISA: NBP1-05049 binds free PP in solution. NBP1-05049 reacts in ELISA with PP coated directly onto the microtiter well. WB: NBP1-05049 can be used in Western blotting.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for Pancreatic Polypeptide/PP Antibody (6) - BSA Free

• INN
• Obinepitide
• pancreatic polypeptide (ppy)
• pancreatic polypeptide PNPPP
• pancreatic polypeptide Y
• Pancreatic Polypeptide
• pancreatic prohormone
• PNP
• PP
• PPY

Background

Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPY