Western blot shows lysates of human placenta tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human PSG Pan Specific Monoclonal Antibody (Catalog # MAB6799) followed by HRP-conjugated Anti-Mouse IgG ...read more
PSG was detected in immersion fixed paraffin-embedded sections of human placenta using Mouse Anti-Human PSG Pan Specific Monoclonal Antibody (Catalog # MAB6799) at 15 µg/mL overnight at 4 °C. Tissue was stained ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Sterile PBS to a final concentration of 0.5 mg/mL.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Pan PSG Antibody (684701) [Unconjugated]
Pregnancy-specific beta-1-glycoprotein 1 (PSG-1),
also called SP1, PSbG1 or B1G1 and designated CD66f, is a 54-72 kDa,
419 amino acid (aa) secreted glycoprotein of the human PSG family within the
CEA (carcinoembryonic antigen) superfamily. PSG-1 shares limited aa sequence
identity with mouse PSGs, but 84-91% aa sequence identity with human PSG-3, -4,
-6, -7, and -8. Potential isoforms of 417-428 aa vary at the extreme
C-terminus. PSG-1 is produced by syncytiotrophoblast cells and its
concentration increases in maternal plasma as pregnancy progresses. Low plasma
PSG-1 in the first or early second trimester has been correlated with fetal
growth restriction. Expression of PSGs has also been detected in choriocarcinomas,
hydatiform moles, ovarian adenocarcinomas, and breast tumors. During pregnancy,
PSG-1 may play role in placental vascular morphogenesis and creation of an
anti-inflammatory uterine environment.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Publications for Pan PSG Antibody (MAB6799)(1)
We have publications tested in 1 confirmed species: Human.
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