Pan PSG Antibody (684701) [Unconjugated]

Images

 
Western blot shows lysates of human placenta tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human PSG Pan Specific Monoclonal Antibody (Catalog # MAB6799) followed by HRP-conjugated Anti-Mouse IgG ...read more
PSG was detected in immersion fixed paraffin-embedded sections of human placenta using Mouse Anti-Human PSG Pan Specific Mono­clonal Antibody (Catalog # MAB6799) at 15 µg/mL overnight at 4 °C. Tissue was stained ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
684701
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

Pan PSG Antibody (684701) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human PSG-1
Val36-Pro419
Accession # P11464
Specificity
Detects human PSG-1, -2, -3, -5 and -6 in Western blots.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PSG1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
  • Immunohistochemistry 8-25 ug/mL
Publications
Read Publication using
MAB6799 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Pan PSG Antibody (684701) [Unconjugated]

  • pan-PSG
  • PSG

Background

Pregnancy-specific beta-1-glycoprotein 1 (PSG-1), also called SP1, PSbG1 or B1G1 and designated CD66f, is a 54-72 kDa, 419 amino acid (aa) secreted glycoprotein of the human PSG family within the CEA (carcinoembryonic antigen) superfamily. PSG-1 shares limited aa sequence identity with mouse PSGs, but 84-91% aa sequence identity with human PSG-3, -4, -6, -7, and -8. Potential isoforms of 417-428 aa vary at the extreme C-terminus. PSG-1 is produced by syncytiotrophoblast cells and its concentration increases in maternal plasma as pregnancy progresses. Low plasma PSG-1 in the first or early second trimester has been correlated with fetal growth restriction. Expression of PSGs has also been detected in choriocarcinomas, hydatiform moles, ovarian adenocarcinomas, and breast tumors. During pregnancy, PSG-1 may play role in placental vascular morphogenesis and creation of an anti-inflammatory uterine environment.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PSG-1 Antibody (MAB6799)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


Filter By Application
WB
(1)
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Filter By Species
Human
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for PSG-1 Antibody (MAB6799) (0)

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Secondary Antibodies

 

Isotype Controls

Additional Pan PSG Products

Pan PSG MAB6799

Bioinformatics Tool for PSG-1 Antibody (MAB6799)

Discover related pathways, diseases and genes to PSG-1 Antibody (MAB6799). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Bioinformatics

Gene Symbol PSG1
Entrez
Uniprot