PACE4/PCSK6 Antibody - BSA Free

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Immunohistochemistry-Paraffin: PACE4 Antibody [NB110-55609] - Analysis of anti-PACE4 antibody with human brain, cortex.

Product Details

Summary
Reactivity Hu, Rb, Pm, PmSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
0.7 mg/ml

Order Details

PACE4/PCSK6 Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 16 amino acid peptide from internal region of human PACE4/PCSK6.
Epitope
internal domain of human protein
Specificity
Human PACE4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Monkey (100%), Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PCSK6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 - 15 ug/ml
Application Notes
.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Mouse (88%), Rat (88%), Bovine (88%), Canine (88%), Equine (88%), Porcine (88%), Opossum (88%), Bat (81%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
0.7 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PACE4/PCSK6 Antibody - BSA Free

  • EC 3.4.21
  • EC 3.4.21.61
  • EC 3.4.21.75
  • PACE4
  • PACE4/PCSK6
  • PACE4EC 3.4.21.-
  • Paired basic amino acid cleaving enzyme 4
  • paired basic amino acid cleaving system 4
  • PCSK6
  • Proprotein Convertase 6
  • proprotein convertase subtilisin/kexin type 6
  • SPC4
  • SPC4subtilisin-like protease
  • Subtilisin/kexin-like protease PACE4
  • Subtilisin-like proprotein convertase 4

Background

PACE4 is a Serine S8 type protease that cleaves precursor proteins at paired basic amino acid processing sites. Several PACE4 substrates have been identified, including transforming growth factor beta-related proteins, proalbumin and von Willebrand factor. At least eight alternatively spliced transcript variants encoding different isoforms have been reported. In mouse, PACE4 has been shown to increase tumor cell invasiveness, and thus enhance tumor progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PCSK6
Entrez