PACE4/PCSK6 Products

Description

The protein encoded by the PACE4 gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Bioinformatics

Uniprot	NP_002561 Human NP_002561.1 Human NP_612195 Human P29122 Human
Product By Gene ID	5046
Alternate Names	EC 3.4.21 EC 3.4.21.61 EC 3.4.21.75 PACE4EC 3.4.21.- Paired basic amino acid cleaving enzyme 4 paired basic amino acid cleaving system 4 proprotein convertase subtilisin/kexin type 6 SPC4subtilisin-like protease Subtilisin/kexin-like protease PACE4 Subtilisin-like proprotein convertase 4