Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Mouse Polyclonal
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
Species: Hu
Applications: IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Species: Hu
Applications: AC
Description
The protein encoded by the PACE4 gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)
Bioinformatics
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
5046 |
| Alternate Names |
- EC 3.4.21.75
- Subtilisin-like proprotein convertase 4
- EC 3.4.21.61
- Paired basic amino acid cleaving enzyme 4
- EC 3.4.21
- paired basic amino acid cleaving system 4
- PACE4EC 3.4.21.-
- SPC4subtilisin-like protease
- Subtilisin/kexin-like protease PACE4
- proprotein convertase subtilisin/kexin type 6
|
Bioinformatics Tool for PACE4/PCSK6
Discover related pathways, diseases and genes to PACE4/PCSK6. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
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