P2Y11/P2RY11 Antibody

Images

 
Immunohistochemistry-Paraffin: P2Y11/P2RY11 Antibody [NLS867] - Analysis of anti-P2RY11 / P2Y11 antibody with human brain, glioblastoma.
Immunohistochemistry-Paraffin: P2Y11/P2RY11 Antibody [NLS867] - Analysis of anti-P2RY11 / P2Y11 antibody with dendritic cells using this antibody at 8 ug/ ml.

Product Details

Summary
Reactivity Hu, Mk, PmSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

P2Y11/P2RY11 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from 3rd extracellular domain of human P2RY11 / P2Y11.
Specificity
Human P2RY11 / P2Y11. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
P2RY11
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 3 ug/ml to 16 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (94%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for P2Y11/P2RY11 Antibody

  • P2RY11
  • P2Y11
  • P2Y11P2Y purinoceptor 11
  • purinergic receptor P2Y, G-protein coupled, 11
  • purinergic receptor P2Y11

Background

P2Y11, the only Purinergic Receptor that acts via cAMP, may be involved in the differentiation of immunocytes. Immature and mature dendritic cells express P2Y and P2X subtypes, including P2Y11, which are coupled to increases in intracellular Ca2+, membrane depolarization, and secretion of inflammatory cytokines. It has been suggested that ATP/P2Y11 contributes to sympathetic stimulation of renin, as well as to renin responses after tissue damage, such as that which occurs with kidney disease and myocardial infarct. Intergenic splicing between the P2Y11 and SSF1 genes changes gene expression, the first case involving a GPCR Communi et al., 2001. Prototypes for this cluster have been chosen to be uniquely P2Y11. P2Y11 has been reported in monocyte-derived dendritic cells, lymphocytes from patients with chronic lymphocytic leukemia, brain, heart, kidney, liver, skeletal muscle, spleen, and testis. ESTs have been isolated from normal human prostate, pancreas, and pooled brain, lung, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-30741
Species: Hu, Mu, Rt, GP
Applications: ICC/IF, IHC, IHC-Fr, IHC-P
NB110-39032
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-32870
Species: Hu, Ch
Applications: WB, IHC, IHC-P, IP
NBP2-15104
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
AF5866
Species: Hu
Applications: WB, IHC
NBP1-32470
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-Fr, IHC-P
NLS5011
Species: Hu, Mk, Pm
Applications: IHC-P
NLS877
Species: Hu, Mk, Pm
Applications: IHC, IHC-P, ICC
NBP2-33870
Species: Hu, Fe
Applications: ICC/IF, IHC, IHC-P
H00005025-B01P
Species: Hu
Applications: WB, Flow, ICC/IF, IHC
NB100-1658
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
NBP2-22203
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
NBP1-85740
Species: Hu, Po
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-19655
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P

Publications for P2Y11/P2RY11 Antibody (NLS867) (0)

There are no publications for P2Y11/P2RY11 Antibody (NLS867).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for P2Y11/P2RY11 Antibody (NLS867) (0)

There are no reviews for P2Y11/P2RY11 Antibody (NLS867). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

View specific protocols for P2Y11/P2RY11 Antibody (NLS867): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for P2Y11/P2RY11 Antibody (NLS867) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional P2Y11/P2RY11 Products

Bioinformatics Tool for P2Y11/P2RY11 Antibody (NLS867)

Discover related pathways, diseases and genes to P2Y11/P2RY11 Antibody (NLS867). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for P2Y11/P2RY11 Antibody (NLS867)

Discover more about diseases related to P2Y11/P2RY11 Antibody (NLS867).
 

Pathways for P2Y11/P2RY11 Antibody (NLS867)

View related products by pathway.

PTMs for P2Y11/P2RY11 Antibody (NLS867)

Learn more about PTMs related to P2Y11/P2RY11 Antibody (NLS867).
 

Research Areas for P2Y11/P2RY11 Antibody (NLS867)

Find related products by research area.

Blogs on P2Y11/P2RY11

There are no specific blogs for P2Y11/P2RY11, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our P2Y11/P2RY11 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol P2RY11
Entrez