P2Y11/P2RY11 Antibody (505214) [Alexa Fluor® 647]

HEK293 human embryonic kidney cell line transfected with either (A) human P2Y11/P2RY11 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human P2Y11/P2RY11 Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB9305R). Quadrant markers were set based on control antibody staining (Catalog # IC002R). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu
• Applications: Flow
• Clone: 505214
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

P2Y11/P2RY11 Antibody (505214) [Alexa Fluor® 647] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human P2Y11/P2RY11
  Accession # Q96G91
• Specificity: Stains human P2Y11/P2RY11 transfectants but not irrelevant transfectants in flow cytometry.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 5 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for P2Y11/P2RY11 Antibody (505214) [Alexa Fluor® 647]

• P2RY11
• P2Y11
• P2Y11P2Y purinoceptor 11
• purinergic receptor P2Y, G-protein coupled, 11
• purinergic receptor P2Y11

Background

P2RY11 belongs to the family of G protein-coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. P2RY11 is coupled to the stimulation of thephosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts,resulting from intergenic splicing between P2RY11 and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. Variants in the P2RY11 gene have been associated with narcolepsy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for P2Y11/P2RY11 Antibody (FAB9305R)(1)

Publication using FAB9305R

• Z Zhang, K Le, D La Placa, B Armstrong, MM Miller, JE Shively CXCR2 specific endocytosis of immunomodulatory peptide LL-37 in human monocytes and formation of LL-37 positive large vesicles in differentiated monoosteophils Bone Rep, 2019-12-13;12(0):100237. 2019-12-13 [PMID: 31886324] (ICC, Human)

Bioinformatics

• Uniprot:
  • Q96G91()