OXTR Antibody - BSA Free

Immunohistochemistry-Paraffin: OXTR Antibody - BSA Free [NBP1-02410] - Human Ganglion

• Reactivity: Hu, Mu, Rt, Bv, Pm, Pm, Sh
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

OXTR Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: A 20 aa synthetic peptide within the N-terminus extracellular domain of human OXTR.
• Epitope: N-Terminus extracellular domain
• Specificity: Human OXTR. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DOK3 (50%).
• Predicted Species: Mouse (95%), Rat (90%), Sheep (90%), Primate (100%), Monkey (95%), Bovine (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OXTR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10-20 ug/ml
• Application Notes: IHC-P: validated with heat induced antigen retrieval in pH 6.0 citrate buffer..

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Elephant (95%), Panda (90%), Bat (85%), Canine (85%), Marmoset (80%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for OXTR Antibody - BSA Free

• OT-R
• OXTR
• oxytocin receptor

Background

The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for OXTR Antibody (NBP1-02410). (Showing 1 - 1 of 1 FAQ).

1. I need to know the sequence of the immunogen peptide used to make Oxytocin Receptor Antibody (NBP1-02410). I am trying to find an antibody to stain this receptor in ants, and without knowing which sequence was used to raise the antibody, I cannot know whether it might cross react. Here is the sequence: >Cbir_04764 (amino acid sequence): 388 residues MSYDLSSSSLPLSLSLPSSPSSSSSPSSLEVSDDLRDEYLARWEIAVLTSIFLITIIGNGLVLFALYARRCYQRRKFTRMYFFILHLSIADLLTGLLDVLPQLAWDITFRFQGGAVLCKLIKFGQPFGLYLSSYILTVTAMDRYYAICHPFSYCAVTSRRSKMMVYGAWVLAAILCVPQVFVFSYKEISPGVWECWATFYLKYGERAYITWYSVTQFLLPFIVLVYTYTQICRSIWTSGKMSGVVDFKQGNKASFSLRNRDPFISKALINTIKQTIVVVSLYIITSIPFIGCELWATWDPKASTSPFFTGAAFTILSLLNSLTSCVNPWIYFAFNRELRAALTNFFCRKKDYSLTYDIDAHQNASDVPSTTSSFISRISRLASSKIFG
   • The amino acird range of the immunogen used to generate this peptide falls within amino acids 1-50 of the human protein according to NP_000907.2. Unfortunately these proteins are so divergent that I can not recommend NBP1-02410 for use in ants.

Bioinformatics

• Gene Symbol: OXTR
• Entrez:
  • 5021(Human)
• Uniprot:
  • P30559()