Osteocrin Antibody (311417) [Alexa Fluor® 594]

• Reactivity: Hu, Mu
• Applications: WB, IP
• Clone: 311417
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 594

Osteocrin Antibody (311417) [Alexa Fluor® 594] Summary

• Immunogen: E. coli-derived recombinant mouse Osteocrin
  Val28-Gly130
  Accession # P61364
• Specificity: Detects human and mouse Osteocrin in direct ELISAs and Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Osteocrin Antibody (311417) [Alexa Fluor® 594]

• Musclin
• Osteocrin
• OSTN

Background

Mouse Osteocrin, also known as Musclin, is a secreted protein that is primarily expressed in bone and muscle. It is synthesized as an 11 kDa proprotein that undergoes proteolytic processing to generate a mature 50 amino acid (5 kDa) C-terminal active peptide. It was found to modulate osteoblast differentation and to regulate glucose metabolism in muscles. Mouse Osteocrin proprotein shares 77% and 78% amino acid sequence identity with the rat and human protein, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.