ORP1 Antibody

Western Blot: ORP1 Antibody [NBP2-59119] - Detection of human OSBPL1A by western blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-OSBPL1A antibody NBP2-59119 used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 3 minutes.

Product Discontinued

ORP1 Antibody Summary

• Immunogen: Maps to a region between 1 and 50
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OSBPL1A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot 1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: Tris-buffered Saline containing 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for ORP1 Antibody

• FLJ10217
• ORP-1oxysterol-binding protein-related protein 1 variant 1
• ORP1oxysterol-binding protein-related protein 1
• OSBP8
• OSBPL1
• OSBPL1B
• OSBP-related protein 1
• oxysterol binding protein-like 1A
• oxysterol binding protein-like 1B
• oxysterol-binding protein-related protein 1 variant 2

Background

Oxysterols are oxygenated derivatives of cholesterol that have a number of biological effects and play a key role in the maintenance of the body cholesterol balance. ORP1 is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that are believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OSBPL1A