Ornithine Carbamoyltransferase Antibody (990421) [DyLight 488]

• Reactivity: Hu
• Applications: IHC
• Clone: 990421
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 488

Ornithine Carbamoyltransferase Antibody (990421) [DyLight 488] Summary

• Immunogen: Synthetic peptide containing human Ornithine Carbamoyltransferase/OTC
  Accession # P00480
• Specificity: Detects human Ornithine Carbamoyltransferase/OTC in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from cell culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Ornithine Carbamoyltransferase Antibody (990421) [DyLight 488]

• EC 2.1.3
• EC 2.1.3.3
• MGC129967
• MGC129968
• MGC138856
• OCTD
• Ornithine Carbamoyltransferase
• ornithine carbamoyltransferase, mitochondrial
• Ornithine Transcarbamylase
• OTC
• OTCase

Background

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.