Orexin R1/HCRTR1 Antibody

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Immunohistochemistry-Paraffin: Orexin R1/HCRTR1 Antibody [NLS6638] - Analysis of anti-HCRTR1 / Orexin Receptor 1 antibody of rat brain, Purkinje neurons at 3.8 ug/ml.

Product Details

Summary
Reactivity Hu, Po, Bv, Rb, Rt, Bt, Ca, Eq, Mk, PmSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Orexin R1/HCRTR1 Antibody Summary

Immunogen
Synthetic 14 amino acid peptide from 2nd extracellular domain of human HCRTR1 / Orexin Receptor 1.
Specificity
Human HCRTR1 / Orexin Receptor 1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HCRTR2 (64%).
Predicted Species
Rat (93%), Equine (93%), Canine (93%), Primate (93%), Bat (93%), Monkey (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HCRTR1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 3.8 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Platypus (100%), Marmoset (93%), Elephant (93%), Panda (93%), Mouse (86%), Hamster (86%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Orexin R1/HCRTR1 Antibody

  • HCRTR1
  • hypocretin (orexin) receptor 1
  • hypocretin receptor 1
  • Hypocretin receptor type 1
  • hypocretin receptor-1
  • Orexin R1
  • orexin receptor 1
  • orexin receptor type 1
  • orexin receptor-1
  • OrexinR1
  • OX1R
  • ox-1-R
  • ox1-R

Background

OX1R is an Orexin Receptor selective for orexin A. This receptor participates in the feedback mechanism that regulates feeding behavior and sleep. When activated, OX1R stimulates appetite. OX1R has been implicated in narcolepsy, a sleep/wake disorder. Orexin receptor 1 expression has been documented in adrenal and brain. ESTs have been isolated from brain, pancreas, and lung/spleen libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HCRTR1
Entrez
Uniprot