Recombinant Human NUDT2 Protein

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SDS-Page: Recombinant Human NUDT2 Protein [NBP1-50970] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human NUDT2 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-147 of Human NUDT2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MALRACGLII FRRCLIPKVD NNAIEFLLLQ ASDGIHHWTP PKGHVEPGED DLETALRETQ EEAGIEAGQL TIIEGFKREL NYVARNKPKT VIYWLAEVKD YDVEIRLSHE HQAYRWLGLE EACQLAQFKE MKAALQEGHQ FLCSIEA

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
NUDT2
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human NUDT2 Protein

  • Ap4A hydrolase 1
  • Ap4A hydrolase
  • Ap4Aase
  • APAH1Diadenosine 5'-5'''-P1
  • bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
  • bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
  • diadenosine 5'-5''-P1
  • Diadenosine tetraphosphatase
  • EC 3.6.1.17
  • MGC10404
  • Nucleoside diphosphate-linked moiety X motif 2
  • nudix (nucleoside diphosphate linked moiety X)-type motif 2
  • Nudix motif 2
  • P4-tetraphosphate asymmetrical hydrolase
  • P4-tetraphosphate pyrophosphohydrolase

Background

NUDT2 is a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. This protein maintains homeostasis by using water to cleave the metabolite NUDT symmetrically back into its original ATP and AMP molecules. NUDT2 is also active towards other adenosine and diadenosine polyphosphates with four or more phosphate groups, but not towards diadenosine triphosphate. NUDT2 is involved in heat shock and metabolic stress by regulating intracellular dinucleoside polyphosphate concentrations. Recombinant NUDT2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol NUDT2