NRAMP1/SLC11A1 Antibody

Western Blot: NRAMP1/SLC11A1 Antibody [H00006556-B01P] - Analysis of SLC11A1 expression in transfected 293T cell line by SLC11A1 polyclonal antibody. Lane 1: SLC11A1 transfected lysate(19.58 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

NRAMP1/SLC11A1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: SLC11A1 (AAH41787.1, 1 a.a. - 178 a.a.) full-length human protein. MTGDKGPQRLSGSSYGSISSPTSPTSPGPQQAPPRETYLRNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRYHPSVPQLFRPGREQLLLLPPLTSPSQSLFYPAVPSEAGLLPCFPEM
• Specificity: SLC11A1 - solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: SLC11A1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NRAMP1/SLC11A1 Antibody

• natural resistance-associated macrophage protein 1
• LSH
• member 1
• NRAMP 1
• NRAMP1
• NRAMP1solute carrier family 11 (sodium/phosphate symporters), member 1
• NRAMPnatural resistance-associated macrophage protein 1
• SLC11A1
• solute carrier family 11 (proton-coupled divalent metal ion transporters)

Background

This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC11A1
• Entrez:
  • 6556(Human)