Notch-3 Antibody [mFluor Violet 500 SE]

• Reactivity: Mu
• Applications: WB, Flow, IHC, B/N, CyTOF-ready, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: mFluor Violet 500 SE

Notch-3 Antibody [mFluor Violet 500 SE] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Notch-3
  Ala40-Glu468
  Accession # Q61982
• Specificity: Detects mouse Notch‑3 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human
  Notch‑3 is observed and less than 5% cross-reactivity with recombinant rat (rr) Notch-1 and rrNotch-2 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: NOTCH3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • Flow Cytometry
  • Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Notch-3 Antibody [mFluor Violet 500 SE]

• CADASIL
• CASILneurogenic locus notch homolog protein 3
• Notch (Drosophila) homolog 3
• notch 3Notch homolog 3 (Drosophila)
• Notch homolog 3
• Notch3
• Notch-3

Background

The NOTCH3 gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NOTCH3