non-muscle Myosin IIA Antibody

Product Discontinued

non-muscle Myosin IIA Antibody Summary

• Immunogen: Synthetic peptide conjugated to KLH, corresponding to amino acids 1950-1961 of Human non-muscle Myosin IIA.
• Localization: Cytoplasmic
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MYH9
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Microarray
  • Western Blot 1:1000
• Application Notes: WB: Detects a band of approximately 200 kDa.
• Control:

  Jurkat Whole Cell Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 10mM PBS (pH 7.4) and 1.0% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for non-muscle Myosin IIA Antibody

• Cellular myosin heavy chain, type A
• DFNA17
• EPSTS
• FTNSNMMHC-IIA
• MGC104539
• MHANMMHC II-a
• MYH9 variant protein
• MYH9
• Myosin heavy chain 9
• Myosin heavy chain, non-muscle IIa
• myosin, heavy chain 9, non-muscle
• myosin, heavy polypeptide 9, non-muscle
• myosin-9
• NMHC-II-A
• NMMHC II-a
• NMMHCA
• NMMHC-A
• NMMHC-IIA
• Non-muscle myosin heavy chain A
• Non-muscle myosin heavy chain IIa
• nonmuscle myosin heavy chain II-A
• non-muscle myosin heavy polypeptide 9
• Non-muscle Myosin IIA

Background

The non-muscle Myosin IIA gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for non-muscle Myosin IIA Antibody (NB600-1083)(1)

Publication using NB600-1083

• Klingner C, Cherian Av, Fels J et al. Isotropic actomyosin dynamics promote organization of the apical cell cortex in epithelial cells. J. Cell Biol. 2014-10-13 [PMID: 25313407] (ICC/IF, WB)

Bioinformatics

• Gene Symbol: MYH9
• Entrez:
  • 481280(Canine)
  • 4627(Human)
  • 25745(Rat)
• Uniprot:
  • P35579(Human)