NKG2E/KLRC3 Antibody [DyLight 488]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 488

NKG2E/KLRC3 Antibody [DyLight 488] Summary

• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human NKG2E/KLRC3
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KLRC3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for NKG2E/KLRC3 Antibody [DyLight 488]

• killer cell lectin-like receptor subfamily C, member 3
• NK cell receptor E
• NKG2-E type II integral membrane protein
• NKG2E
• NKG2-E-activating NK receptor
• NKG2ENKG2-E

Background

KLRC3 codes for a protein that works as a receptor for the recognition of MHC molecules by natural killers, and in some cases cytotoxic T-cells. KLRC3 is a gene made up of two isoforms, measuring 240 and 257 amino acids in length, and weighing approximately 27 and 29 kDa respectively. Studies have been done on diseases and disorders relating to this gene including monkeypox. KLRC3 has also been shown to have interactions with KLRD1, TYROBP, HLA-A, and HLA-C in pathways such as the antigen processing and natural killer cell mediated cytotoxicity pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLRC3