NK2R Antibody - BSA Free

Western Blot: NK2R Antibody - BSA Free [NBP3-45302] - HeLa cells were subjected to SDS PAGE followed by western blot with ( NK2R Antibody) at dilution of 1:600

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

NK2R Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit NK2R Antibody - BSA Free (NBP3-45302) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: tachykinin receptor 2. (Uniprot# P21452)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TACR2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500-1:2000
• Theoretical MW: 44 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for NK2R Antibody - BSA Free

• Neurokinin A Receptor
• Neurokinin-2 Receptor
• NK2R
• NK2RNK-2 receptor
• NKNAR
• NKNARseven transmembrane helix receptor
• SKR
• SKRneurokinin 2 receptor
• Substance K Receptor
• substance-K receptor
• TAC2R
• TAC2Rsubstance K receptor
• Tachykinin Receptor 2
• tachykinin receptor 2NK-2R
• TACR2

Background

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TACR2