NK2R Products

Antibodies
NK2R Antibody
NK2R Antibody
NB100-58993
Species: Hu, Equine, Primate, Porcine, Rabbit, Monkey
Applications: ELISA, IHC-P
Host: Rabbit Polyclonal
NK2R Antibody
NK2R Antibody
NBP1-00244
Species: Hu, Bv
Applications: PEP-ELISA
Host: Goat Polyclonal
NK2R Antibody
NK2R Antibody
NB100-58992
Species: Hu, Po, Bovine, Canine, Equine, Guinea Pig, Hamster, Rabbit, Rat
Applications: ELISA, IHC-P
Host: Rabbit Polyclonal
RNAi
NK2R RNAi
NK2R RNAi
H00006865-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Bioinformatics

Uniprot Human
Human
Product By Gene ID 6865
Alternate Names
  • substance-K receptor
  • Neurokinin A receptor
  • TAC2Rsubstance K receptor
  • NKNARseven transmembrane helix receptor
  • SKRneurokinin 2 receptor
  • NK2RNK-2 receptor
  • tachykinin receptor 2NK-2R

Pathways for NK2R

View related products by pathway and learn more about each of the pathways below.

Sperm Motility
Localization
Secretion

Research Areas for NK2R

Find related products by research area and learn more about each of the different research areas below.

GPCR
Neuronal Cell Markers
Neuroscience
Neurotransmission

Bioinformatics Tool for NK2R

Discover related pathways, diseases and genes to NK2R. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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