NISCH Antibody (2C8) - Azide and BSA Free

Sandwich ELISA: NISCH Antibody (2C8) [H00011188-M02] - Detection limit for recombinant GST tagged NISCH is approximately 0.3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 2C8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

NISCH Antibody (2C8) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse NISCH Antibody (2C8) - Azide and BSA Free (H00011188-M02) is a monoclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: NISCH (AAH56900, 1246 a.a. ~ 1345 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LTGSTPMQVVTCLTRDSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPSEEEIGDLTFTVAQKMAEPEKAPAL
• Specificity: NISCH - nischarin
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: NISCH
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NISCH Antibody (2C8) - Azide and BSA Free

• hIRAS
• I-1 receptor candidate protein
• I-1
• I-1FLJ14425
• I1R candidate protein
• I1R
• Imidazoline receptor 1
• imidazoline receptor antisera selected
• Imidazoline receptor antisera-selected protein
• imidazoline receptor candidate
• Imidazoline-1 receptor candidate protein
• Imidazoline-1 receptor
• IR1
• IRAS
• IRASFLJ40413
• KIAA0975
• KIAA0975FLJ90519
• NISCH
• nischarin

Background

Mouse Nischarin (NISCH) has been shown to interact with the alpha-5 subunit of integrin and inhibit cell migration. Its human homologue (imidazoline receptor antisera-selected (IRAS)), contains an NH2-terminal extension and is a larger protein of 1504 amino acids consisting of an NH2-terminal PX domain, 5 putative leucine-rich repeats, a predicted coiled-coil domain, and a long COOH-terminal region. It has the ability to homo-oligomerize via its coiled-coil region. The PX domain of IRAS is essential for association with phosphatidylinositol 3-phosphate-enriched endosomal membranes. NISCH may serve as a functional imidazoline I1-receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NISCH
• Entrez:
  • 11188(Human)
• Uniprot:
  • AAH56900(Human)