Neuregulin-1/NRG1 Antibody [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 532

Neuregulin-1/NRG1 Antibody [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant human NRG1 Isoform GGF2
  Gly51-Cys248
  Accession # NP_039256
• Specificity: Detects human NRG1 Isoform GGF2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross‑reactivity with recombinant human (rh) NRG‑1 alpha EGF domain, rhNRG1-beta 1 extracellular domain, rhNRG1-beta 1 EGF domain, rhSMDF, and recombinant mous
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neuregulin-1/NRG1 Antibody [Alexa Fluor® 532]

• ARIA
• GGF2
• GGFglial growth factor
• Heregulin-1
• HGL
• HGLneu differentiation factor
• HRG
• HRG1
• HRG1-alpha
• HRG1-beta 1
• HRGAneuregulin 1 type IV beta 1a
• MST131
• MSTP131
• NDFheregulin, alpha (45kD, ERBB2 p185-activator)
• neuregulin 1 type IV beta 3
• neuregulin 1
• Neuregulin1
• Neuregulin-1
• NRG1
• pro-neuregulin-1, membrane-bound isoform
• Pro-NRG1
• sensory and motor neuron derived factor
• SMDF

Background

By alternative splicing, the Neuregulin 1 gene ecodes at least 10 secreted or membrane-bound proteins, all of which contain an EGF-like domain. Neuregulin 1 isoforms bind and signal via the ErbB family of receptor tyrosine kinases. Isoform GGF2 contains a unique kringle-like domain, plus Ig and EGF-like domains that are also present in multiple Neuregulin 1 isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.