NEK4 Antibody [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Applications: IHC, IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 488

NEK4 Antibody [Alexa Fluor™ Plus 488] Summary

• Immunogen: The immunogen for this product maps to a region between residue 350 and 400 of human NIMA (never in mitosis gene a)-related kinase 4 using the numbering given in entry NP_003148.2 (GeneID 6787).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NEK4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NEK4 Antibody [Alexa Fluor™ Plus 488]

• EC 2.7.11
• Never in mitosis A-related kinase 4
• NIMA (never in mitosis gene a)-related kinase 4
• NimA-related protein kinase 4
• NRK2EC 2.7.11.1
• pp12301
• serine/threonine kinase 2
• serine/threonine protein kinase-2
• Serine/threonine-protein kinase 2
• serine/threonine-protein kinase Nek4
• Serine/threonine-protein kinase NRK2
• STK2MGC33171

Background

Belonging to the NEK Ser/Thr protein kinase family, NEK4 plays a significant role in the cell cycle, cell division, mitosis and protein phosphorylation process. More specifically, NEK4 can be found in the nucleus, and acts exclusively upon threonine residues. Molecular Functions of NEK4 include ATP binding, metal ion binding and protein serine/threonine kinase activity. Common diseases for NEK4 include adenocarcinoma, cancer, polycystic ovary syndrome, epithelial neoplasia, coffin-lowry syndrome, bipolar disorder, retinitis and malaria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NEK4