NEI3 Antibody - BSA Free

Western Blot: NEI3 Antibody [NB100-441] - Analysis of NEI3 using IMG-4151 at 1:500 dilution on 50 ug of human testis lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

NEI3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit NEI3 Antibody - BSA Free (NB100-441) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Residues 164-177 (LRAESEVKKQKGRMLG) of the human NEI3 protein. 85% sequence identity to mouse and rat.
• Specificity: This is specific for human NEI3.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NEIL3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: This antibody may be used for Western blot. No other assays have been tested. Suggested working dilutions: * Western Blot - 1:500 *The investigator should determine the optimal working dilution for a specific application. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 67.7 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  NEI3 Overexpression Lysate

Reactivity Notes

Hu

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for NEI3 Antibody - BSA Free

• DNA glycosylase FPG2
• DNA glycosylase hFPG2
• DNA glycosylase/AP lyase Neil3
• EC 3.2.2.-
• EC 4.2.99.18
• endonuclease 8-like 3
• Endonuclease VIII-like 3
• FGP2
• FLJ10858
• FPG2
• hFPG2
• hNEI3
• nei endonuclease VIII-like 3 (E. coli)
• NEI3
• Nei-like protein 3

Background

Prokaryotes and lower eukaryotes possess redundant activities that remove the plethora of oxidative DNA base damages produced during normal oxidative metabolism and which have been associated with cancer and aging. Thus far, only one oxidized pyrimidine-specific DNA glycosylase has been identified in humans, hNthl. HNEI3 is one of three new putative human DNA glycosylases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NEIL3
• Entrez:
  • 55247(Human)