NCOR2 Antibody

Product Discontinued

NCOR2 Antibody Summary

• Immunogen: A synthetic peptide from the human SMRT protein corresponding to amino acids 80-92 (QELHLRPESHSYL).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: NCOR2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Alternate Names for NCOR2 Antibody

• CTG repeat protein 26
• CTG26
• CTG26nuclear receptor co-repressor 2
• FLJ25011
• NCOR2
• N-CoR2
• nuclear receptor corepressor 2
• retinoic-acid-receptor-associated corepressor
• silencing mediator for retinoid and thyroid hormone receptors
• SMAP270
• SMRT
• SMRTE
• SMRTE-tau
• SMRTT3 receptor-associating factor
• TNRC14
• TRAC
• TRAC1
• TRAC-1

Background

Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NCOR2