Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC, IP, ChIP
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Sheep Polyclonal
Species: Hu
Applications: WB, IHC, ChIP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription.
Bioinformatics
| Uniprot |
Human Human |
| Product By Gene ID |
9612 |
| Alternate Names |
- CTG repeat protein 26
- CTG26nuclear receptor co-repressor 2
- FLJ25011
- N-CoR2
- nuclear receptor corepressor 2
- retinoic-acid-receptor-associated corepressor
- silencing mediator for retinoid and thyroid hormone receptors
- SMAP270
- SMRTE
- SMRTE-tau
- SMRTT3 receptor-associating factor
- TNRC14
- TRAC
- TRAC1
|
Related NCOR2 Blog Posts
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NCOR & EZH2 in Muscular Dystrophy
Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur... Read more.
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Muscular Dystrophy Regulation: Ezh2, NCoR-1
Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur... Read more.
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