NCOR2 Antibody

Immunocytochemistry/Immunofluorescence: NCOR2 Antibody [NBP1-85386] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.

Immunohistochemistry-Paraffin: NCOR2 Antibody [NBP1-85386] - Staining of human cerebellum shows nuclear positivity in purkinje cells, cells in molecular layer and cells in granular layer.

Product Discontinued

NCOR2 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: EEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKV
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NCOR2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  NCOR2 Protein (NBP1-85386PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for NCOR2 Antibody

• CTG repeat protein 26
• CTG26
• CTG26nuclear receptor co-repressor 2
• FLJ25011
• NCOR2
• N-CoR2
• nuclear receptor corepressor 2
• retinoic-acid-receptor-associated corepressor
• silencing mediator for retinoid and thyroid hormone receptors
• SMAP270
• SMRT
• SMRTE
• SMRTE-tau
• SMRTT3 receptor-associating factor
• TNRC14
• TRAC
• TRAC1
• TRAC-1

Background

Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for NCOR2 Antibody (NBP1-85386). (Showing 1 - 1 of 1 FAQ).

1. Could I please get the concentration of NCOR2 antibody (NBP1-85386)?
   • The concentration of our current lot of NBP1-85386, lot A75438, is 0.1 mg/ml.

Bioinformatics

• Gene Symbol: NCOR2