NCOR2 Antibody (1542)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clone
1542
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

View Available Conjugates

NCOR2 Antibody (1542) Summary

Immunogen
A synthetic peptide from the human SMRT protein corresponding to amino acids 994-1005 (ASASDPHREKTQ) coupled to KLH.
Specificity
This is specific for SMRT.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NCOR2
Purity
Protein G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunoprecipitation
Application Notes
Clone H7 recognizes the Silencing Mediator Retinoid and Thyroid receptors (SMRT) gene product, a 168 kDa nuclear protein. WB: Predicted molecular weight: 274 kDa.
Publications
Read Publications using
NB200-309 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for NCOR2 Antibody (1542)

  • CTG repeat protein 26
  • CTG26
  • CTG26nuclear receptor co-repressor 2
  • FLJ25011
  • NCOR2
  • N-CoR2
  • nuclear receptor corepressor 2
  • retinoic-acid-receptor-associated corepressor
  • silencing mediator for retinoid and thyroid hormone receptors
  • SMAP270
  • SMRT
  • SMRTE
  • SMRTE-tau
  • SMRTT3 receptor-associating factor
  • TNRC14
  • TRAC
  • TRAC1
  • TRAC-1

Background

Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for NCOR2 Antibody (NB200-309)(3)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for NCOR2 Antibody (NB200-309) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for NCOR2 Antibody (NB200-309)

Discover related pathways, diseases and genes to NCOR2 Antibody (NB200-309). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Research Areas for NCOR2 Antibody (NB200-309)

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Blogs on NCOR2.

Muscular Dystrophy Regulation: Ezh2, NCoR-1
Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur...  Read full blog post.

NCOR & EZH2 in Muscular Dystrophy
Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur...  Read full blog post.

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Bioinformatics

Gene Symbol NCOR2
Entrez