NCCRP1 Antibody (5C.6)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-2071
    • Availability
      Product Discontinued

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NCCRP1 Antibody (5C.6) Summary

Immunogen
Purified NCC cells from catfish.
Specificity
Nonspecific Cytotoxic Cell (5C.6)
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
NCCRP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100 - 1:2000
  • Flow Cytometry 1:10 - 1:1000
  • Immunoprecipitation 1:10 - 1:500
  • Inhibition Activity
  • Western Blot 10 ug/ml

Reactivity Notes

Tilapia and Catfish.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS with 1 mg/ml BSA
Preservative
0.05% Sodium Azide
Concentration
0.73 mg/ml
Purity
Immunogen affinity purified

Alternate Names for NCCRP1 Antibody (5C.6)

  • LOC342897
  • NCCRP-1
  • non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
  • nonspecific cytotoxic cell receptor protein 1 homolog
  • non-specific cytotoxic cell receptor protein 1 homolog

Background

Non-specific cytotoxic cells (NCCs) in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. One such property is that NCC/natural killer (NK)/lymphokine activated killer (LAK) cells express spontaneous, non-major histocompatibility complex restricted cytotoxic activity. NCC and LAK lyse a variety of transformed murine and human B-cell, T-cell and myeloid targets. A 32 kDa membrane protein [non-specific cytotoxic cell receptor protein (NCCRP-1)] expressed by NCC and certain mammalian NK/LAK cells mediates this cytotoxicity. NCCRP-1 is evolutionarily conserved and is found in species ranging from marine and freshwater teleosts to higher mammals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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    Bioinformatics

    Gene Symbol NCCRP1
    Entrez
    Uniprot