NCCRP1 Antibody (5C.6) Summary
| Immunogen |
Purified NCC cells from catfish. |
| Specificity |
Nonspecific Cytotoxic Cell (5C.6) |
| Isotype |
IgM |
| Clonality |
Monoclonal |
| Host |
Mouse |
| Gene |
NCCRP1 |
| Purity |
Immunogen affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- ELISA 1:100 - 1:2000
- Flow Cytometry 1:10 - 1:1000
- Immunoprecipitation 1:10 - 1:500
- Inhibition Activity
- Western Blot 10 ug/ml
|
Reactivity Notes
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles. |
| Buffer |
PBS with 1 mg/ml BSA |
| Preservative |
0.05% Sodium Azide |
| Concentration |
0.73 mg/ml |
| Purity |
Immunogen affinity purified |
Alternate Names for NCCRP1 Antibody (5C.6)
Background
Non-specific cytotoxic cells (NCCs) in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. One such property is that NCC/natural killer (NK)/lymphokine activated killer (LAK) cells express spontaneous, non-major histocompatibility complex restricted cytotoxic activity. NCC and LAK lyse a variety of transformed murine and human B-cell, T-cell and myeloid targets. A 32 kDa membrane protein [non-specific cytotoxic cell receptor protein (NCCRP-1)] expressed by NCC and certain mammalian NK/LAK cells mediates this cytotoxicity. NCCRP-1 is evolutionarily conserved and is found in species ranging from marine and freshwater teleosts to higher mammals.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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