Napsin A Antibody (TMU-Ad02) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clone
TMU-Ad02
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Napsin A Antibody (TMU-Ad02) [DyLight 405] Summary

Immunogen
Synthetic peptide corresponding to the N-terminus of human NAPSA [UniProt# O96009]
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NAPSA
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This NAPSA antibody is useful for Western blot and Immunohistochemistry on formalin-fixed, paraffin embedded sections. In WB a band can be seen around 45-50 kDa.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Napsin A Antibody (TMU-Ad02) [DyLight 405]

  • Asp 4
  • ASP4
  • Aspartyl protease 4
  • EC 3.4.23
  • EC 3.4.23.-
  • EC 3.4.23.15
  • EC 3.4.23.3
  • EC 3.4.23.5
  • KAP
  • Kdap
  • NAP1napsin-A
  • NAPA
  • NAPApronapsin A
  • NAPSA
  • napsin A aspartic peptidase
  • Napsin A
  • Napsin-1
  • SNAPA
  • TA01/TA02

Background

NAPSA (Napsin A) is an aspartic proteinase that belongs to peptidase A1 family (NAPSA, cathepsins D and E, renin, pepsin, gastricsin, and bovine chymosin) and it is primarily expressed in lung and kidney, and at a very low levels in spleen as well as in peripheral blood leukocytes. NAPSA's expression is regulated by TTF-1 which also regulates the expression of surfactant protein B. Inside the lung, NAPSA is expressed in alveolar type II pneumocytes where it colocalize with prosurfactant B protein as well as surfactant B in the lamellar bodies, and has been suggested to be involved in N-terminal/C-terminal processing of prosurfactant B protein. NAPSA is also localized in intra-alveolar macrophages, probably as a result of phagocytosis. In renal tissues, NAPSA is expressed in the proximal tubules, where it is suggested to function as a lysosomal protease involved in protein catabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, IHC, IHC-P

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NB110-68133B
DyLight 488 Labeled NB110-68133G
DyLight 550 Labeled NB110-68133R
DyLight 650 Labeled NB110-68133C
FITC Labeled NB110-68133F
HRP Labeled NB110-68133H

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Bioinformatics

Gene Symbol NAPSA
Entrez