NANS Antibody

Western Blot: NANS Antibody [H00054187-B01P] - Analysis of NANS expression in human pancreas.

Western Blot: NANS Antibody [H00054187-B01P] - Analysis of NANS expression in transfected 293T cell line by NANS polyclonal antibody. Lane 1: NANS transfected lysate(39.49 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

NANS Antibody Summary

• Immunogen: NANS (NP_061819.2, 1 a.a. - 359 a.a.) full-length human protein. MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKFNRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKVKIPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: NANS
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NANS Antibody

• EC 2.5.1.56
• EC 2.5.1.57
• N-acetylneuraminate synthase
• N-acetylneuraminate-9-phosphate synthase
• N-acetylneuraminic acid phosphate synthase
• N-acetylneuraminic acid synthasesialic acid phosphate synthase
• SASsialic acid synthase

Background

NANS encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NANS
• Uniprot:
  • NP_061819.2(Human)