Recombinant Human N myc interactor Protein

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SDS-Page: N myc interactor Recombinant Protein [NBP1-50958]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human N myc interactor Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-307 of Human N myc interactor

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEADKDDTQQ ILKEHSPDEF IKDEQNKGLI DEITKKNIQLK KEIQKLETE LQEATKEFQI KEDIPETKMK FLSVETPEND SQLSNISCSF QVSSKVPYEI QKGQALITFE KEEVAQNVVS MSKHHVQIKDV NLEVTAKPV PLNSGVRFQV YVEVSKMKIN VTEIPDTLRE DQMRDKLELS FSKSRNGGGE VDRVDYDRQS GSAVITFVEI GVADKILKKKEYPLYINQTC HRVTVSPYTE IHLKKYQIFS GTSKRTVLLT GMEGIQMDEE IVEDLINIHF QRAKNGGGEV DVVKCSLGQP HIAYFEE

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
NMI
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
37.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human N myc interactor Protein

  • Nmi
  • N-myc (and STAT) interactor
  • N-myc and STAT interactor
  • N-myc interactor
  • N-myc-interactor

Background

N-myc-interactor, also known as NMI, is a member of the oncogene Myc family. The Myc family of oncogenes is thought to play an important role in cell proliferation, differentiation, and neoplastic transformation. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. Recombinant human NMI protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol NMI