Myosin heavy chain 14 Antibody (Poly6212)

Product Discontinued

Myosin heavy chain 14 Antibody (Poly6212) Summary

• Immunogen: Recombinant
• Specificity: Myosin heavy chain
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: MYH14
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:400

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A or G purified

Alternate Names for Myosin heavy chain 14 Antibody (Poly6212)

• DFNA4
• DFNA4A
• FP17425
• MHC16
• MYH14
• MYH17
• myosin, heavy chain 14, non-muscle
• NMHC II-C
• NMHC-II-C
• PNMHH

Background

Myosin heavy chain is an actin-based motor protein with an approximate molecular weight of 223 kD. Myosin heavy chain can be split into 1 light meromysin and 1 heavy meromysin chain (and further into 2 globular subfragments and 1 rod-shaped subfragment). This protein is highly expressed in muscle. Motor proteins that convert chemical energy derived from ATP hydrolysis into mechanical force that drives motile processes such as cytokinesis, vesicular transport, and cellular locomotion. Myosin heavy chain is modified by acetylation in cysteine residues in the S1 domain for myosin ATPase activity. Muscle myosin is a hexameric protein consisting of 2 heavy chain subunits and 2 alkali light chain subunits and 2 regulatory light chain subunits that forms filaments.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYH14
• Entrez:
  • 79784(Human)
• Uniprot:
  • Q7Z406(Human)