MYO18A Antibody

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Immunoprecipitation: MYO18A Antibody [NB100-79839] - Detection of Human Myo18A/Myosin XVIIIA by Western Blot of Immunoprecipitates. Samples: RIPA whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
 

Independent Antibodies

       

Order Details

MYO18A Antibody Summary

Immunogen
The immunogen this antibody was made to, maps to a region between residue 300 and 350 of human myosin 18A using the numbering given in entry NP_510880.2 (GeneID 399687).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MYO18A
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2-5 mcg/mg lysate
Application Notes
This antibody has not performed satisfactorily when used for WB of Myo18A/Myosin XVIIIA in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Myo18A/Myosin XVIIIA.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MYO18A Antibody

  • KIAA0216DKFZp686L0243
  • MAJN
  • Molecule associated with JAK3 N-terminus
  • myosin 18A
  • Myosin containing a PDZ domain
  • myosin containing PDZ domain
  • myosin XVIIIA
  • myosin-XVIIIa
  • MysPDZ
  • SP-A receptor subunit SP-R210 alphaS
  • SPR210

Background

Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE)-rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid-associated lung collectin that mediates innate and adaptive immune responses in the lungs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MYO18A
Entrez
Uniprot