MXRA5 Antibody

Immunohistochemistry-Paraffin: MXRA5 Antibody [NBP1-46122] - 5ug/ml staining of Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu
• Applications: WB, IHC, IHC-P, PEP-ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

MXRA5 Antibody Summary

• Immunogen: Peptide with sequence C-QAETTTLDQDHLET corresponding to internal region according to NP_056234.2.
• Epitope: internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: MXRA5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Peptide ELISA Detection limit 1:16000
  • Western Blot 1 ug/ml
• Application Notes: Western blot: Preliminary experiments in Human Brain (Hippocampus) and Skeletal Muscle lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for MXRA5 Antibody

• Adhesion protein with leucine-rich repeats and immunoglobulin domains relatedto perlecan
• adlican
• DKFZp564I1922
• matrix-remodeling-associated protein 5
• matrix-remodelling associated 5

Background

The MXRA5 gene encodes a 2,828 amino acid long, 312 kDA matrix-remodeling-associated protein 5 that contains seven leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. Additionally, MXRA5 has a pseudogene on chromosome Y. This gene interacts with genes EIF1B and UBC. MXRA5 has been linked to chronic myocardial ischemia and colon cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for MXRA5 Antibody (NBP1-46122)(1)

Publication using NBP1-46122

• Fu GK, Wang JT, Yang J et al. Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. Genomics 2004-07-01 [PMID: 15203218]

Bioinformatics

• Gene Symbol: MXRA5
• Entrez:
  • 25878(Human)
• Uniprot:
  • NP_056234.2(Human)