MTAC2D1 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

MTAC2D1 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human TC2N.
  
  

  Source: E. coli

  Amino Acid Sequence: IKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRF

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: TC2N
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-89900.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 33 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for MTAC2D1 Recombinant Protein Antigen

• C2 calcium-dependent domain containing 1
• C2CD1
• chromosome 14 open reading frame 47
• FLJ36557
• membrane targeting (tandem) C2 domain containing 1
• Membrane targeting tandem C2 domain-containing protein 1
• MTAC2D1
• Tac2-NC14orf47
• tandem C2 domains nuclear protein
• tandem C2 domains, nuclear
• Tandem C2 protein in nucleus

Background

The TC2N (MTAC2D1) gene encodes a tandem C2 domains nuclear protein that in isoform 1 is 490 amino acids long and 55 kDA and in isoform 2is 426 amino acids long at 47 kDA. This gene interacts with the gene ELAVL1 and has been linked to thrombosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TC2N