MST1/STK4 Antibody [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: mFluor Violet 500 SE

MST1/STK4 Antibody [mFluor Violet 500 SE] Summary

• Immunogen: E. coli-derived recombinant human MST1/STK4
  Lys285-Asp443
  Accession # Q13043
• Specificity: Detects human MST1/STK4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human MST2 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: STK4
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MST1/STK4 Antibody [mFluor Violet 500 SE]

• kinase responsive to stress 2
• KRS2
• Mammalian STE20-like protein kinase 1
• mammalian sterile 20-like 1
• MST1
• serine/threonine-protein kinase 4
• Serine/threonine-protein kinase Krs-2
• STE20-like kinase MST1
• STK4
• YSK3

Background

The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STK4