MPV17 Antibody

Images

 
Western Blot: MPV17 Antibody [NBP1-52097] - (2ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

MPV17 Antibody Summary

Immunogen
Peptide with sequence C-QRALAAHPWKVQ corresponding to internal region according to NP_002428.1.
Epitope
C-QRALAAHPWKVQ
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MPV17
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 - 3 ug/ml
  • Immunohistochemistry 5 - 10 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx. 19 kDa band observed in human brain (frontal cortex) lysates (calculated MW of 19.7 kDa band according to NP_002428.1). An additional band of unknown identity was also consistently observed at 26 kDa. This band was successfully blocked by incubation with the immunizing peptide. IHC-P: Human liver shows heavy textured cystoplasm staining in hepatocytes, consistent with mitochondia.
Publications
Read Publication using NBP1-52097.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine, Bovine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MPV17 Antibody

  • human homolog of glomerulosclerosis and nephrotic syndrome
  • MpV17 mitochondrial inner membrane protein
  • murine homolog, glomerulosclerosis
  • protein Mpv17

Background

This gene encodes a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species. Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MPV17 Antibody (NBP1-52097)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MPV17
Entrez
Uniprot