Mouse TWEAK/TNFSF12 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse TWEAK/TNFSF12 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Tnfsf12

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse TWEAK/TNFSF12 DuoSet ELISA, 15 Plate

• APO3 ligand
• APO3LMGC20669
• DR3LGTWEAKAPO3/DR3 ligand
• MGC129581
• TNF-related weak inducer of apoptosis
• TNFSF12
• tumor necrosis factor (ligand) superfamily, member 12
• tumor necrosis factor ligand superfamily member 12
• TWEAK

Background

TWEAK is a type II transmembrane protein belonging to the TNF superfamily. The extracellular domains of human and mouse TWEAK share 89% amino acid sequence identity. A soluble form of TWEAK is generated from the membrane-associated molecule by proteolytic cleavage after Arg 93, suggesting that TWEAK may have long-range effects. TWEAK is expressed widely in many tissues and cells.

Publications for TWEAK/TNFSF12 (DY1237)(5)

Publications using DY1237

• AJ Vesting, A Jais, P Klemm, L Steuernage, P Wienand, M Fog-Tonnes, H Hvid, AL Schumacher, C Kukat, H Nolte, T Georgomano, J Altmüller, M Pasparakis, A Schmidt, M Krüger, MS Supprian, A Waisman, BK Straub, N Raschzok, M Bernier, AL Birkenfeld, N Hövelmeyer, JC Brüning, FT Wunderlich NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition Molecular Metabolism, 2022-11-07;66(0):101626. 2022-11-07 [PMID: 36356831] (Mouse)
• K Browne, E Zhang, JK Sullivan, KS Evonuk, TM DeSilva, TN Jorgensen Lupus-prone B6.Nba2 male and female mice display anti-DWEYS reactivity and a neuropsychiatric phenotype Brain, Behavior, and Immunity, 2021-02-17;0(0):. 2021-02-17 [PMID: 33607233] (Mouse)
• Lucas Cheadle, Samuel A. Rivera, Jasper S. Phelps, Katelin A. Ennis, Beth Stevens, Linda C. Burkly et al. Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism Neuron 2020-11-01 [PMID: 32931754] (Mouse)
• KS Tummala, M Brandt, A Teijeiro, O Graña, RF Schwabe, C Perna, N Djouder Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells Cell Rep, 2017-04-18;19(3):584-600. 2017-04-18 [PMID: 28423321] (Mouse)
• Al-Sawaf O, Fragoulis A, Rosen C, Kan Y, Sonmez T, Pufe T, Wruck C Nrf2 protects against TWEAK-mediated skeletal muscle wasting. Sci Rep, 2014-01-10;4(0):3625. 2014-01-10 [PMID: 24406502] (Mouse)

FAQs for TWEAK/TNFSF12 (DY1237). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: Tnfsf12