Mouse Total MMP-9 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse Total MMP-9 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Mmp9

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Total MMP-9 DuoSet ELISA, 15 Plate

• 92 kDa gelatinase
• 92 kDa type IV collagenase
• CLG4B
• EC 3.4.24
• EC 3.4.24.35
• Gelatinase B
• GELB
• macrophage gelatinase
• MANDP2
• matrix metallopeptidase 9
• matrix metalloproteinase 9
• matrix metalloproteinase-9
• MMP9
• MMP-9
• type V collagenase

Background

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

Publications for MMP-9 (DY6718)(13)

Publications using DY6718

• Hamadi, N;Al?Salam, S;Beegam, S;Zaaba, N;Elzaki, O;Nemmar, A; Chronic Exposure to Two Regimens of Waterpipe Smoke Elicits Lung Injury, Genotoxicity, and Mitochondrial Impairment with the Involvement of MAPKs Activation in Mice International journal of molecular sciences 2025-01-06 [PMID: 39796284] (Mouse)
• Zhu, W;Han, L;Wu, Y;Tong, L;He, L;Wang, Q;Yan, Y;Pan, T;Shen, J;Song, Y;Shen, Y;Zhu, Q;Zhou, J; Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9 Respiratory research 2023-11-25 [PMID: 38007424] (Transgenic Mouse, Mouse)
• G Feigelman, E Simanovich, P Brockmeyer, MA Rahat Knocking-Down CD147/EMMPRIN Expression in CT26 Colon Carcinoma Forces the Cells into Cellular and Angiogenic Dormancy That Can Be Reversed by Interactions with Macrophages Biomedicines, 2023-03-02;11(3):. 2023-03-02 [PMID: 36979746] (Mouse)
• NM Wenger, L Qiao, T Nicola, Z Nizami, X Xu, KA Willis, N Ambalavana, A Gaggar, CV Lal Efficacy of a Probiotic and Herbal Supplement in Models of Lung Inflammation Microorganisms, 2022-10-28;10(11):. 2022-10-28 [PMID: 36363728] (Mouse)
• HJ Lee, CH Yoon, HJ Kim, JH Ko, JS Ryu, DH Jo, JH Kim, D Kim, JY Oh Ocular microbiota promotes pathological angiogenesis and inflammation in sterile injury-driven corneal neovascularization Mucosal Immunology, 2022-08-19;0(0):. 2022-08-19 [PMID: 35986099] (Mouse)
• A Conforti, T Wahlers, A Paunel-Gör Neutrophil extracellular traps modulate inflammatory markers and uptake of oxidized LDL by human and murine macrophages PLoS ONE, 2021-11-19;16(11):e0259894. 2021-11-19 [PMID: 34797846] (Mouse)
• M Hafner, S Paukner, WW Wicha, B Hrva?i?, M Cedilak, I Faraho, SP Gelone Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model PLoS ONE, 2021-09-29;16(9):e0237659. 2021-09-29 [PMID: 34587166] (Mouse)
• SE Huang, E Sulistyowa, YY Chao, BN Wu, ZK Dai, JH Hsu, JL Yeh In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis Biomedicines, 2021-05-28;9(6):. 2021-05-28 [PMID: 34071594] (Mouse)
• L Shaban, GT Nguyen, BD Mecsas-Fax, KD Swanson, S Tan, J Mecsas Yersinia pseudotuberculosis�YopH targets SKAP2-dependent and independent signaling pathways to block neutrophil antimicrobial mechanisms during infection PLoS Pathog., 2020-05-11;16(5):e1008576. 2020-05-11 [PMID: 32392230] (Mouse)
• B Burger, CMC Kühl, T Candreva, RDS Cardoso, JR Silva, BG Castelucci, SR Consonni, HL Fisk, PC Calder, MAR Vinolo, HG Rodrigues Oral administration of EPA-rich oil impairs collagen reorganization due to elevated production of IL-10 during skin wound healing in mice Sci Rep, 2019-06-24;9(1):9119. 2019-06-24 [PMID: 31235718] (Mouse)
• C Li, I Maillet, C Mackowiak, C Viala, F Di Padova, M Li, D Togbe, V Quesniaux, Y Lai, B Ryffel Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells Cell Death Dis, 2017-04-06;8(4):e2735. 2017-04-06 [PMID: 28383552] (Mouse)
• Ludewig P, Sedlacik J, Gelderblom M, Bernreuther C, Korkusuz Y, Wagener C, Gerloff C, Fiehler J, Magnus T, Horst A Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke. Circ Res, 2013-06-18;113(8):1013-22. 2013-06-18 [PMID: 23780386] (Mouse)
• Habibzay , M, Saldana , J I, Goulding , J, Lloyd , C M, Hussell , T Altered regulation of Toll-like receptor responses impairs antibacterial immunity in the allergic lung. Mucosal Immunol, 2012-05-02;5(5):524-34. 2012-05-02 [PMID: 22549744] (Mouse)

FAQs for MMP-9 (DY6718). (Showing 1 - 2 of 2 FAQs).

1.  I’m looking for a pair of antibodies to MMP-9 that can be used in a sandwich assay. Do you carry any? 
   • We have 10 primary antibodies for MMP-9 that have been tested in ELISA, seen here.It looks like 2 have been tested for capture (please note the tested species for each of these), seen here.6 have been tested for detection, seen here.
2. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: Mmp9