Mouse/Rat PDGF-AB Quantikine ELISA Kit

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Mouse/Rat PDGF-AB Quantikine ELISA Kit Summary

Background
The Quantikine Mouse/Rat PDGF-AB Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse/rat PDGF-AB in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant rat PDGF-AB and antibodies raised against recombinant rat PDGF. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse.../rat PDGF-AB showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse/rat PDGF-AB.
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Specificity
Natural and recombinant mouse and rat PDGF-AB
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
MHD00 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse/Rat PDGF-AB Quantikine ELISA Kit

  • PDGFAB
  • PDGF-AB

Background

The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of four homodimeric proteins, PDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD, and one heterodimeric protein, PDGF-AB. Members of this protein family act mainly on connective tissue. The dimeric isoforms of PDGF are expressed by different cell types and at different times during embryonic development. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms that contain a PDGF/VEGF cysteine knot domain. Only PDGF-C and PDGF-D, also named spinal cord-derived growth factors SCDGF and SCDGF-B, also contain an N-terminal CUB domain. Mature PDGF dimers bind and induce the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta).

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for PDGF-AB (MHD00)(9)

We have publications tested in 3 confirmed species: Mouse, Rat, Porcine.

We have publications tested in 1 application: ELISA (Standard).


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ELISA (Standard)
(1)
All Applications
Filter By Species
Mouse
(5)
Rat
(3)
Porcine
(1)
All Species
Showing Publications 1 - 9 of 9.
Publications using MHD00 Applications Species
JD Koerner, DZ Markova, GD Schroeder, BP Calio, A Shah, CW Brooks, AR Vaccaro, DG Anderson, CK Kepler The local cytokine and growth factor response to rhBMP-2 after spinal fusion Spine J, 2018;0(0):. 2018 [PMID: 29550606] (ELISA (Standard), Rat) ELISA (Standard) Rat
Adiponectin enhances bone marrow mesenchymal stem cell resistance to flow shear stress through AMP-activated protein kinase signaling Sci Rep, 2016;6(0):28752. 2016 [PMID: 27418435] (Rat) Rat
Schledzewski K, Geraud C, Arnold B, Wang S, Grone HJ, Kempf T, Wollert KC, Straub BK, Schirmacher P, Demory A, Schonhaber H, Gratchev A, Dietz L, Thierse HJ, Kzhyshkowska J, Goerdt S Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors. J. Clin. Invest., 2011;121(2):703-14. 2011 [PMID: 21293057] (Mouse) Mouse
Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis. Eur. J. Pharmacol., 2008;590(1):400-8. 2008 [PMID: 18598692] (Mouse) Mouse
Kilian O, Wenisch S, Karnati S, Baumgart-Vogt E, Hild A, Fuhrmann R, Jonuleit T, Dingeldein E, Schnettler R, Franke RP Observations on the microvasculature of bone defects filled with biodegradable nanoparticulate hydroxyapatite. Biomaterials, 2008;29(24):3429-37. 2008 [PMID: 18501961] (Porcine) Porcine
Paintlia AS, Paintlia MK, Singh AK, Singh I Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis. Mol. Pharmacol., 2008;73(5):1381-93. 2008 [PMID: 18239032] (Rat) Rat
He M, Kubo H, Ishizawa K, Hegab AE, Yamamoto Y, Yamamoto H, Yamaya M The role of the receptor for advanced glycation end-products in lung fibrosis. Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(6):L1427-36. 2007 [PMID: 17951314] (Mouse) Mouse
Ebos JM, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy. Proc. Natl. Acad. Sci. U.S.A., 2007;104(43):17069-74. 2007 [PMID: 17942672] (Mouse) Mouse
Panoskaltsis-Mortari A, Tram KV, Price AP, Wendt CH, Blazar BR A new murine model for bronchiolitis obliterans post-bone marrow transplant. Am. J. Respir. Crit. Care Med., 2007;176(7):713-23. 2007 [PMID: 17575098] (Mouse) Mouse

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